Issue 93, 2016
From the journal:

Chemical Communications

Ultrasensitive detection of microRNAs using catalytic hairpin assembly coupled with enzymatic repairing amplification†

Chong-Hua Zhang,a   Ying Tang,a   Ying-Ying Sheng,a   Hui Wang,a   Zhan Wu*a  and  Jian-Hui Jiang*a  

* Corresponding authors

a State Key Laboratory of Chemo-Biosensing & Chemometrics, College of Chemistry & Chemical Engineering, Hunan University, Changsha 410082, China
E-mail: jianhuijiang@hnu.edu.cn, wuzhan1002@gmail.com
Fax: +86-731-88821916
Tel: +86-731-88664085

Abstract

A novel isothermal nucleic acid amplification technology is developed by coupling catalytic hairpin assembly with enzymatic repairing amplification as a highly sensitive and selective platform for miRNA detection.

Graphical abstract: Ultrasensitive detection of microRNAs using catalytic hairpin assembly coupled with enzymatic repairing amplification

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Article information

DOI
https://doi.org/10.1039/C6CC07116C
Article type
Communication
Submitted
31 Aug 2016
Accepted
25 Oct 2016
First published
25 Oct 2016

Chem. Commun., 2016,52, 13584-13587

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Ultrasensitive detection of microRNAs using catalytic hairpin assembly coupled with enzymatic repairing amplification

C. Zhang, Y. Tang, Y. Sheng, H. Wang, Z. Wu and J. Jiang, Chem. Commun., 2016, 52, 13584 DOI: 10.1039/C6CC07116C

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