Issue 84, 2016

Enantioselective formation of cyclopropane spiroindenes from benzofulvenes by phase transfer catalysis

Abstract

The enantio- and diastereoselective formation of indenes spirofused to highly substituted cyclopropanes is described. The application of a new cinchona alkaloid derived ammonium salt in a phase transfer catalysis setup facilitates high selectivity and excellent yields at low catalyst loadings (0.1–1.0 mol%).

Graphical abstract: Enantioselective formation of cyclopropane spiroindenes from benzofulvenes by phase transfer catalysis

Supplementary files

Article information

Article type
Communication
Submitted
01 Sep 2016
Accepted
27 Sep 2016
First published
27 Sep 2016

Chem. Commun., 2016,52, 12474-12477

Enantioselective formation of cyclopropane spiroindenes from benzofulvenes by phase transfer catalysis

B. S. Donslund, N. I. Jessen, J. B. Jakobsen, A. Monleón, R. P. Nielsen and K. A. Jørgensen, Chem. Commun., 2016, 52, 12474 DOI: 10.1039/C6CC07170H

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements