Issue 84, 2016
From the journal:

Chemical Communications

A cupric ion triggered DNA diode based on a tandem linkage–cleavage reaction†

Ting Cao,a   Ji Nie,a   Liang-Yuan Cai,a   Xiao-Hui Zhang,a   De-Wen Zhang, ORCID logo *bc   Ying-Lin Zhou*a  and  Xin-Xiang Zhang*a  

* Corresponding authors

a Beijing National Laboratory for Molecular Sciences (BNLMS), MOE Key Laboratory of Bioorganic Chemistry and Molecular Engineering, College of Chemistry, Peking University, Beijing 100871, China
E-mail: zhouyl@pku.edu.cn, zxx@pku.edu.cn
Fax: +86-10-62754112
Tel: +86-10-62754112

b School of Engineering and Materials Science, Queen Mary University of London, Mile End Road, London E1 4NS, UK

c China Academy of Engineering Physics, Mianyang, Sichuan, China
E-mail: zhangdewenpku@163.com

Abstract

Based on click chemistry and DNAzyme, we constructed for the first time a cupric ion triggered DNA diode using a tandem linkage–cleavage process, which could occur in order in a programmable and autonomous manner. This DNA diode is a new DNA functional element and can precisely control the translation direction of information.

Graphical abstract: A cupric ion triggered DNA diode based on a tandem linkage–cleavage reaction

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Article information

DOI
https://doi.org/10.1039/C6CC07293C
Article type
Communication
Submitted
06 Sep 2016
Accepted
21 Sep 2016
First published
21 Sep 2016

Chem. Commun., 2016,52, 12490-12493

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A cupric ion triggered DNA diode based on a tandem linkage–cleavage reaction

T. Cao, J. Nie, L. Cai, X. Zhang, D. Zhang, Y. Zhou and X. Zhang, Chem. Commun., 2016, 52, 12490 DOI: 10.1039/C6CC07293C

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