Issue 85, 2016

Direct synthesis of nitroaryl acetylenes from acetylenes and nitroarenes via oxidative nucleophilic substitution of hydrogen

Abstract

Acetylenic carbanions add to nitroarenes (dinitrobenzenes, nitropyridines, etc.) to form σH-adducts that are subsequently oxidized by DDQ according to the oxidative nucleophilic substitution of hydrogen (ONSH) pathway to give nitroaryl acetylenes.

Graphical abstract: Direct synthesis of nitroaryl acetylenes from acetylenes and nitroarenes via oxidative nucleophilic substitution of hydrogen

Supplementary files

Article information

Article type
Communication
Submitted
13 Sep 2016
Accepted
27 Sep 2016
First published
28 Sep 2016
This article is Open Access
Creative Commons BY license

Chem. Commun., 2016,52, 12650-12652

Direct synthesis of nitroaryl acetylenes from acetylenes and nitroarenes via oxidative nucleophilic substitution of hydrogen

R. Bujok and M. Mąkosza, Chem. Commun., 2016, 52, 12650 DOI: 10.1039/C6CC07475H

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