Issue 95, 2016
From the journal:

Chemical Communications

Bio-inspired engineering proteinosomes with a cell-wall-like protective shell by self-assembly of a metal-chelated complex†

Dongyue Su,a   Xiaoman Liu,*a   Lei Wang,a   Chao Ma,a   Hui Xie,b   Hao Zhang,b   Xianghe Meng,b   Yudong Huanga  and  Xin Huang*a  

* Corresponding authors

a MIIT Key Laboratory of Critical Materials Technology for New Energy Conversion and Storage, State Key Laboratory of Urban Water Resource and Environment, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin, China
E-mail: liuxiaoman@hit.edu.cn, xinhuang@hit.edu.cn

b State Key Laboratory of Robotics and Systems, Harbin Institute of Technology, 2 Yikuang, 150080 Harbin, China

Abstract

A cell-wall-like shell is constructed around proteinosomes by coordination complexes of tannic acid and Fe3+, which endows the engineered proteinosomes with an enhanced Young's modulus of the membrane, protease resistant ability, EDTA-mediated release of loaded DNA, and electrostatic gated encapsulated enzyme activity, as well as antioxidant capacity.

Graphical abstract: Bio-inspired engineering proteinosomes with a cell-wall-like protective shell by self-assembly of a metal-chelated complex

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Article information

DOI
https://doi.org/10.1039/C6CC07655F
Article type
Communication
Submitted
20 Sep 2016
Accepted
01 Nov 2016
First published
03 Nov 2016

Chem. Commun., 2016,52, 13803-13806

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Bio-inspired engineering proteinosomes with a cell-wall-like protective shell by self-assembly of a metal-chelated complex

D. Su, X. Liu, L. Wang, C. Ma, H. Xie, H. Zhang, X. Meng, Y. Huang and X. Huang, Chem. Commun., 2016, 52, 13803 DOI: 10.1039/C6CC07655F

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