Issue 99, 2016
From the journal:

Chemical Communications

Neutral red as a specific light-up fluorescent probe for i-motif DNA†

Lijun Xu,ab   Jine Wang,*a   Na Sun,a   Min Liu,a   Yi Cao,a   Zhili Wanga  and  Renjun Pei*a  

* Corresponding authors

a Key Laboratory of Nano-Bio Interface, Division of Nanobiomedicine, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou 215123, China
E-mail: rjpei2011@sinano.ac.cn

b University of Chinese Academy of Sciences, Beijing 100049, China

Abstract

We report a specific light-up fluorescent probe for i-motif DNA for the first time. Compared with the previously reported probes, neutral red could selectively interact with an i-motif and show a significant increase in its fluorescence. This feature makes it advantageous for designing label-free fluorescent sensing systems.

Graphical abstract: Neutral red as a specific light-up fluorescent probe for i-motif DNA

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Article information

DOI
https://doi.org/10.1039/C6CC07674B
Article type
Communication
Submitted
21 Sep 2016
Accepted
17 Nov 2016
First published
17 Nov 2016

Chem. Commun., 2016,52, 14330-14333

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Neutral red as a specific light-up fluorescent probe for i-motif DNA

L. Xu, J. Wang, N. Sun, M. Liu, Y. Cao, Z. Wang and R. Pei, Chem. Commun., 2016, 52, 14330 DOI: 10.1039/C6CC07674B

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