A highly sensitive and selective miRNA detection approach based on a small circular probe and dual signal amplification has been reported. We successfully applied the assay for quantitative let-7a detection in cell lysates and the results agreed well with those of qRT-PCR.
Y. Tang, X. He, Z. Zhou, J. Tang, R. Guo and X. Feng, Chem. Commun., 2016, 52, 13905 DOI: 10.1039/C6CC07719F
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