Issue 2, 2016

Bactericidal mechanism of nanopatterned surfaces

Abstract

The quest to design and fabricate new antibacterial surfaces is an important task to meet the urgent demands of biomedical applications. Recently, a mechanical mechanism for killing adherent bacteria was discovered on nanopatterned surfaces, but there is a lack of understanding of the bactericidal mechanism. Here we present a quantitative thermodynamic model to study the bactericidal mechanism of nanopatterned surfaces through analyzing the total free energy change of bacterial cells. By comparing the bacterial cells on a flat surface and nanopatterned surface, our theoretical results reveal that cicada wing-like nanopatterned surfaces have more effective bactericidal properties than flat surfaces because a patterned surface leads to a drastic increase of the contact adhesion area. Our model also reveals some details of the influence mechanism, and gives some important information about how to improve the bactericidal properties through designing the morphology of the patterned surface.

Graphical abstract: Bactericidal mechanism of nanopatterned surfaces

Supplementary files

Article information

Article type
Paper
Submitted
21 Sep 2015
Accepted
01 Dec 2015
First published
01 Dec 2015

Phys. Chem. Chem. Phys., 2016,18, 1311-1316

Bactericidal mechanism of nanopatterned surfaces

X. Li, Phys. Chem. Chem. Phys., 2016, 18, 1311 DOI: 10.1039/C5CP05646B

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements