Dopamine polymerization promoted by a catecholase biomimetic CuII(μ-OH)CuII complex containing a triazine-based ligand

Abstract

We describe herein the catecholase-like catalytic activity and dopamine polymerization by using a dinuclear [LCu^II(μ-OH)₂Cu^II](ClO₄)₂ (1) complex where L is the dinucleating triazine-based ligand 6-chloro-N²,N²,N⁴,N⁴-tetrakis(pyridin-2-ylmethyl)-1,3,5-triazine-2,4-diamine. The kinetic parameters (k_cat = 0.318 s⁻¹, K_M = 1.6 × 10⁻³ mol L⁻¹, and k_cat/K_M = 198.8 L s⁻¹ mol⁻¹), mechanistic insights into the oxidation of 3,5-di-tert-butyl catechol and early characterization of poly(dopamine) are presented.