Issue 13, 2016

Development of GSK's NMR guides – a tool to encourage the use of more sustainable solvents

Abstract

Residual solvents often appear as nuisance signals in experimental NMR spectra, and many chemists turn to well-known literature sources to quickly identify such peaks. While these publications are very useful, they do not currently include many solvents exemplified in green chemistry-related literature. This work provides a single compiled reference for NMR chemical shifts of 80 solvents in each of 6 deuterated NMR solvents. The overall green chemistry assessments, as reached via the methodology of the GSK Solvent Sustainability Guide, are displayed on these charts.

Graphical abstract: Development of GSK's NMR guides – a tool to encourage the use of more sustainable solvents

Supplementary files

Article information

Article type
Paper
Submitted
16 Feb 2016
Accepted
15 Apr 2016
First published
15 Apr 2016

Green Chem., 2016,18, 3867-3878

Development of GSK's NMR guides – a tool to encourage the use of more sustainable solvents

H. E. Gottlieb, G. Graczyk-Millbrandt, G. G. A. Inglis, A. Nudelman, D. Perez, Y. Qian, L. E. Shuster, H. F. Sneddon and R. J. Upton, Green Chem., 2016, 18, 3867 DOI: 10.1039/C6GC00446F

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