Issue 7, 2016
From the journal:

Lab on a Chip

A contact-lens-on-a-chip companion diagnostic tool for personalized medicine†

Allan Guan, ORCID logo a   Yi Wang,b   K. Scott Phillips*b  and  Zhenyu Li*a  

* Corresponding authors

a Department of Biomedical Engineering, The George Washington University, 800 22nd Street NW, Washington, DC 20052, USA
E-mail: zhenyu@gwu.edu

b Division of Biology, Chemistry and Materials Science, Office of Science and Engineering Laboratories, Center for Devices and Radiological Health, U.S. Food and Drug Administration, 10903 New Hampshire Avenue, Silver Spring, MD 20993, USA
E-mail: Kenneth.Phillips@fda.hhs.gov

Abstract

We present a novel, microfluidic platform that integrates human tears (1 μL) with commercial contact lens materials to provide personalized assessment of lens care solution performance. This device enabled the detection of significant differences in cleaning and disinfection outcomes between subjects and between biofilms vs. planktonic bacteria.

Graphical abstract: A contact-lens-on-a-chip companion diagnostic tool for personalized medicine

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Article information

DOI
https://doi.org/10.1039/C6LC00034G
Article type
Communication
Submitted
10 Jan 2016
Accepted
16 Feb 2016
First published
16 Feb 2016

Lab Chip, 2016,16, 1152-1156

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A contact-lens-on-a-chip companion diagnostic tool for personalized medicine

A. Guan, Y. Wang, K. S. Phillips and Z. Li, Lab Chip, 2016, 16, 1152 DOI: 10.1039/C6LC00034G

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