Single-layer MoS2 nanosheet grafted upconversion nanoparticles for near-infrared fluorescence imaging-guided deep tissue cancer phototherapy

Jianyu Han; Hongping Xia; Yafeng Wu; Shik Nie Kong; Amudha Deivasigamani; Rong Xu; Kam M. Hui; Yuejun Kang

doi:10.1039/C6NR00150E

You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page.

Single-layer MoS₂ nanosheet grafted upconversion nanoparticles for near-infrared fluorescence imaging-guided deep tissue cancer phototherapy†

Jianyu Han,‡^a Hongping Xia,‡^b Yafeng Wu,‡^a Shik Nie Kong,^b Amudha Deivasigamani,^b Rong Xu,*^a Kam M. Hui*^b and Yuejun Kang*^c

Author affiliations

* Corresponding authors

^a School of Chemical and Biomedical Engineering, Nanyang Technological University, 62 Nanyang Drive, Singapore 637459, Singapore
E-mail: rxu@ntu.edu.sg

^b Division of Cellular and Molecular Research, National Cancer Centre, 11 Hospital Drive, Duke-NUS Medical School, Singapore 169610, Singapore
E-mail: cmrhkm@nccs.com.sg

^c Faculty of Materials and Energy, Institute for Clean Energy and Advanced Materials, Southwest University, 2 Tiansheng Road, Beibei, Chongqing, China
E-mail: yjkang@swu.edu.cn

Abstract

A multifunctional nanostructure is prepared by covalently grafting upconversion nanoparticles (UCNPs) with chitosan functionalized MoS₂ (MoS₂–CS) and folic acid (FA) and then loading phthalocyanine (ZnPc) on the surface of MoS₂, which integrates photodynamic therapy (PDT) with photothermal therapy (PTT) and upconversion luminescence imaging into one system for enhanced antitumor efficiency.

Download options Please wait...

Supplementary files

Supplementary information PDF (2048K)

Article information

DOI: https://doi.org/10.1039/C6NR00150E
Article type: Communication
Submitted: 07 Jan 2016
Accepted: 22 Mar 2016
First published: 23 Mar 2016

Download Citation

Nanoscale, 2016,8, 7861-7865

Permissions

Request permissions

Single-layer MoS₂ nanosheet grafted upconversion nanoparticles for near-infrared fluorescence imaging-guided deep tissue cancer phototherapy

J. Han, H. Xia, Y. Wu, S. N. Kong, A. Deivasigamani, R. Xu, K. M. Hui and Y. Kang, Nanoscale, 2016, 8, 7861 DOI: 10.1039/C6NR00150E

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Social activity

Fetching data from CrossRef.
This may take some time to load.

Nanoscale