Issue 36, 2016
From the journal:

Nanoscale

GAG mimetic functionalised solid and mesoporous silica nanoparticles as viral entry inhibitors of herpes simplex type 1 and type 2 viruses†

Edward C. Lee,a   Nicholas Davis-Poynter,*b   Chau T. H. Nguyen,a   Amelia A. Peters,a   Gregory R. Monteith,ac   Ekaterina Strounina,d   Amirali Popat*ac  and  Benjamin P. Ross ORCID logo *a  

* Corresponding authors

a The University of Queensland, School of Pharmacy, Brisbane, QLD 4072, Australia
E-mail: b.ross1@uq.edu.au, a.popat@uq.edu.au

b The University of Queensland, Centre for Children's Health Research, 46 Graham St, South Brisbane, QLD 4101, Australia
E-mail: n.davispoynter@uq.edu.au

c The University of Queensland, Translational Research Institute, Mater Research Institute, 37 Kent St, Woolloongabba, QLD 4102, Australia

d The University of Queensland, Centre for Advanced Imaging, Brisbane, QLD 4072, Australia

Abstract

A glycosaminoglycan mimetic was attached to the surface of solid and mesoporous silica nanoparticles to create novel antiviral agents against herpes simplex type 1 and type 2 viruses. The nanoparticles act as viral entry inhibitors that appear to block viral attachment and penetration into susceptible cells.

Graphical abstract: GAG mimetic functionalised solid and mesoporous silica nanoparticles as viral entry inhibitors of herpes simplex type 1 and type 2 viruses

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C6NR03878F
Article type
Communication
Submitted
13 May 2016
Accepted
27 Aug 2016
First published
30 Aug 2016

Nanoscale, 2016,8, 16192-16196

Permissions

Request permissions

GAG mimetic functionalised solid and mesoporous silica nanoparticles as viral entry inhibitors of herpes simplex type 1 and type 2 viruses

E. C. Lee, N. Davis-Poynter, C. T. H. Nguyen, A. A. Peters, G. R. Monteith, E. Strounina, A. Popat and B. P. Ross, Nanoscale, 2016, 8, 16192 DOI: 10.1039/C6NR03878F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements