Issue 46, 2016
From the journal:

Nanoscale

Nanoparticle-based photoacoustic analysis for highly sensitive lateral flow assays

Yunfei Zhao,a   Yin Huang,a   Xiangwei Zhao,*b   John F. McClellandc  and  Meng Lu*ad  

* Corresponding authors

a Department of Electrical and Computer Engineering, Iowa State University, Ames, Iowa 50011, USA
E-mail: menglu@iastate.edu

b State Key Laboratory of Bioelectronics, Southeast University, Nanjing, Jiangsu 211189, P. R. China
E-mail: xwzhao@iastate.edu

c MTEC Photoacoustics Inc., 3507 Oakland Street, Ames, IA 50014, USA

d Department of Mechanical Engineering, Iowa State University, Ames, Iowa 50011, USA

Abstract

This paper demonstrates a photoacoustics-based lateral flow test that takes advantage of the strong interaction of light and gold nanoparticles to quantitatively detect a disease biomarker. For a commercially available lateral flow test strip, the photoacoustic analysis improved the detection limit by two orders of magnitude compared to colorimetric measurements.

Graphical abstract: Nanoparticle-based photoacoustic analysis for highly sensitive lateral flow assays

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Article information

DOI
https://doi.org/10.1039/C6NR05312B
Article type
Communication
Submitted
04 Jul 2016
Accepted
08 Nov 2016
First published
08 Nov 2016

Nanoscale, 2016,8, 19204-19210

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Nanoparticle-based photoacoustic analysis for highly sensitive lateral flow assays

Y. Zhao, Y. Huang, X. Zhao, J. F. McClelland and M. Lu, Nanoscale, 2016, 8, 19204 DOI: 10.1039/C6NR05312B

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