Issue 16, 2016
From the journal:

Organic & Biomolecular Chemistry

A molecular receptor for zwitterionic phenylalanine†

Francisco Gómez Herrero,a   Omayra H. Rubio,a   Laura M. Monleón,a   Ángel L. Fuentes de Arriba,a   Luís Simón Rubio ORCID logo *b  and  Joaquín R. Morán*a  

* Corresponding authors

a Organic Chemistry Department, University of Salamanca, Plaza de los Caídos 1-5, 37008 Salamanca, Spain
E-mail: romoran@usal.es

b Engineering Chemistry Department, University of Salamanca, Plaza de los Caídos 1-5, 37008 Salamanca, Spain
E-mail: lsimon@usal.es

Abstract

The combination of a 1,3-ketoenol system and two pyridine molecules attached as sulfonamide and carboxamide to a benzofuran skeleton allows the preparation of a novel chiral receptor for zwitterionic phenylalanine association. Interestingly, no crown-ether, urea or guanidinium are necessary to carry out the extraction of amino acids from the aqueous solution, which constitutes a breakthrough in comparison with other receptors for zwitterionic amino acid extraction.

Graphical abstract: A molecular receptor for zwitterionic phenylalanine

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Article information

DOI
https://doi.org/10.1039/C6OB00490C
Article type
Paper
Submitted
03 Mar 2016
Accepted
22 Mar 2016
First published
22 Mar 2016

Org. Biomol. Chem., 2016,14, 3906-3912

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A molecular receptor for zwitterionic phenylalanine

F. G. Herrero, O. H. Rubio, L. M. Monleón, Á. L. Fuentes de Arriba, L. S. Rubio and J. R. Morán, Org. Biomol. Chem., 2016, 14, 3906 DOI: 10.1039/C6OB00490C

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