Nickel catalyzed α-arylation of ketones with aryltrimethylammonium triflates†
Abstract
Nickel-catalyzed α-arylation of ketones involving aromatic C–N cleavage has been accomplished. Intermolecular coupling of aromatic ketones with a variety of aryltrimethylammonium triflates was achieved in the presence of Ni(COD)2, IPr·HCl, and LiOBut, giving α-arylated ketones in reasonable to excellent yields.