Cp*Co(iii)-catalyzed, N–N bond-based redox-neutral synthesis of isoquinolines†
Abstract
We report herein a redox-neutral Cp*Co(III)-catalyzed cyclization of acetophenone N-Boc hydrazones with alkynes for streamlined synthesis of isoquinolines, accomplished via formation of a C–C and a C–N bond along with N–N bond cleavage. Moreover, this rapid approach can be completed in 30 min with yields up to 85%.