Issue 48, 2016, Issue in Progress
From the journal:

RSC Advances

A sensitive polymeric dark quencher-based sensing platform for fluorescence “turn on” detection of proteins†

Ying Lv,ab   Jiatao Wu,ab   Pan Wu,ab   Yu Zong Chen,c   Ying Tan,*b   Chunyan Tan*ab  and  Yuyang Jiangbd  

* Corresponding authors

a Department of Chemistry, Tsinghua University, Beijing 100084, P. R. China

b The Ministry-Province Jointly Constructed Base for State Key Lab-Shenzhen Key Laboratory of Chemical Biology, Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, P. R. China
E-mail: tancy@sz.tsinghua.edu.cn, tan.ying@sz.tsinghua.edu.cn

c Shenzhen Technology and Engineering Laboratory for Personalized Cancer Diagnostics and Therapeutics, Shenzhen Kivita Innovative Drug Discovery Institute, Shenzhen 518055, P. R. China

d Department of Pharmacology and Pharmaceutical Sciences, School of Medicine, Tsinghua University, Beijing 100084, P. R. China

Abstract

A fluorescence “turn on” detection platform for proteins has been developed with high sensitivity and specificity by taking advantage of highly efficient quenching of conjugated polymeric dark quenchers, as well as specific target recognition by either aptamer or peptide substrate probes.

Graphical abstract: A sensitive polymeric dark quencher-based sensing platform for fluorescence “turn on” detection of proteins

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Article information

DOI
https://doi.org/10.1039/C6RA07310G
Article type
Communication
Submitted
20 Mar 2016
Accepted
20 Apr 2016
First published
25 Apr 2016

RSC Adv., 2016,6, 42443-42446

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A sensitive polymeric dark quencher-based sensing platform for fluorescence “turn on” detection of proteins

Y. Lv, J. Wu, P. Wu, Y. Z. Chen, Y. Tan, C. Tan and Y. Jiang, RSC Adv., 2016, 6, 42443 DOI: 10.1039/C6RA07310G

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