Homocoupling of heteroaryl/aryl/alkyl Grignard reagents: I2-promoted, or Ni- or Pd- or Cu- or nano-Fe-based salt catalyzed†
Abstract
Five efficient processes for the homo-coupling of various Grignard reagents including aryl, heteroaryl and aliphatic ones in the presence of I2, Pd(OAc)2, Ni(OAc)2, CuI, and nano-Fe3O4 were developed, respectively.