Issue 115, 2016, Issue in Progress
From the journal:

RSC Advances

Ultra-sensitive diagnosis of orthotopic patient derived hepatocellular carcinoma by Fe@graphene nanoparticles in MRI†

Chao Zhang,ab   Jing Ren,c   Yutong Yang,a   Dunhui Wang,d   Jian He,*b   Da Huo*a  and  Yong Hu*a  

* Corresponding authors

a Institute of Materials Engineering, College of Engineering and Applied Sciences, Nanjing University, Jiangsu, P. R. China
E-mail: hvyong@nju.edu.cn, allicinhonda@163.com

b Department of Radiology, Drum Tower Hospital, School of Medicine, Nanjing University, Jiangsu, P. R. China
E-mail: hjxueren@163.com

c The State Key Laboratory of Pharmaceutical Biotechnology, Division of Immunology, Medical School, Nanjing University, Nanjing 210093, China

d Department of Physics, Nanjing University, Nanjing 210093, P. R. China

Abstract

We synthesized core–shell structured Fe/G-PEG NPs composed of an Fe core and a PEGylated graphene, which exhibited superior stability against oxidation, good water dispersity, low cytotoxicity and high magnetic performance. These advantages ensure them as candidates for ultra-sensitive contrast enhanced magnetic resonance imaging agents in vivo.

Graphical abstract: Ultra-sensitive diagnosis of orthotopic patient derived hepatocellular carcinoma by Fe@graphene nanoparticles in MRI

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Article information

DOI
https://doi.org/10.1039/C6RA23511E
Article type
Communication
Submitted
21 Sep 2016
Accepted
30 Nov 2016
First published
30 Nov 2016

RSC Adv., 2016,6, 113919-113923

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Ultra-sensitive diagnosis of orthotopic patient derived hepatocellular carcinoma by Fe@graphene nanoparticles in MRI

C. Zhang, J. Ren, Y. Yang, D. Wang, J. He, D. Huo and Y. Hu, RSC Adv., 2016, 6, 113919 DOI: 10.1039/C6RA23511E

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