Issue 5, 2016
From the journal:

Chemical Science

Construction of spirocarbocycles via gold-catalyzed intramolecular dearomatization of naphthols†

Wen-Ting Wu,a   Ren-Qi Xu,a   Liming Zhang*b  and  Shu-Li You*a  

* Corresponding authors

a State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Lu, Shanghai 200032, China
E-mail: slyou@sioc.ac.cn

b University of California, Santa Barbara, California 93106, USA
E-mail: zhang@chem.ucsb.edu

Abstract

A highly efficient, gold-catalyzed intramolecular dearomatization reaction of naphthols via 5-endo-dig cyclization is described. This facile and direct approach furnishes spirocarbocycles in excellent yields under mild conditions.

Graphical abstract: Construction of spirocarbocycles via gold-catalyzed intramolecular dearomatization of naphthols

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Article information

DOI
https://doi.org/10.1039/C5SC04130A
Article type
Edge Article
Submitted
31 Oct 2015
Accepted
01 Feb 2016
First published
02 Feb 2016
This article is Open Access

All publication charges for this article have been paid for by the Royal Society of Chemistry
Creative Commons BY license

Chem. Sci., 2016,7, 3427-3431

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Construction of spirocarbocycles via gold-catalyzed intramolecular dearomatization of naphthols

W. Wu, R. Xu, L. Zhang and S. You, Chem. Sci., 2016, 7, 3427 DOI: 10.1039/C5SC04130A

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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