One-pot synthesis of magnesium nanoparticles embedded in a chitosan microparticle matrix: a highly biocompatible tool for in vivo cancer treatment

Robert. C. Martin; Erica Locatelli; Yan Li; Paolo Matteini; Ilaria Monaco; Guozhen Cui; Suping Li; Martina Banchelli; Roberto Pini; Mauro Comes Franchini

doi:10.1039/C5TB02499D

One-pot synthesis of magnesium nanoparticles embedded in a chitosan microparticle matrix: a highly biocompatible tool for in vivo cancer treatment†

Robert. C. Martin,^a Erica Locatelli,^b Yan Li,^a Paolo Matteini,^c Ilaria Monaco,^b Guozhen Cui,^a Suping Li,^a Martina Banchelli,^c Roberto Pini^c and Mauro Comes Franchini

*^b

Author affiliations

* Corresponding authors

^a Division of Surgical Oncology, Department of Surgery, University of Louisville, Louisville, USA

^b Department of Industrial Chemistry “Toso MOntanari”, University of Bologna, Via Risorgimento, Bologna, Italy
E-mail: mauro.comesfranchini@unibo.it

^c Institute of Applied Physics “Nello Carrara”, National Research Council of Italy, via Madonna del Piano 10, I-50019 Sesto Fiorentino, Italy

Abstract

A novel highly biocompatible nanosystem made up of a chitosan matrix and filled with magnesium nanoparticles was synthesized using a simple and one-pot strategy, and tested as a promising, well-tolerated tool for photothermal therapy. Moreover, in vivo a proof of concept on hepatocarcinoma-bearing mice is presented.

Journal of Materials Chemistry B

One-pot synthesis of magnesium nanoparticles embedded in a chitosan microparticle matrix: a highly biocompatible tool for in vivo cancer treatment†

Abstract

Supplementary files

Article information

Download Citation

Author version available

Permissions

One-pot synthesis of magnesium nanoparticles embedded in a chitosan microparticle matrix: a highly biocompatible tool for in vivo cancer treatment

Social activity

Search articles by author

Spotlight

Advertisements