Issue 15, 2016
From the journal:

Journal of Materials Chemistry B

Ultrastrong and flexible hybrid hydrogels based on solution self-assembly of chitin nanofibers in gelatin methacryloyl (GelMA)†

P. Hassanzadeh,ab   M. Kazemzadeh-Narbat,cd   R. Rosenzweig,a   X. Zhang,ab   A. Khademhosseini,*cdefg   N. Annabi*cdh  and  M. Rolandi*ab  

* Corresponding authors

a Department of Materials Science and Engineering, University of Washington, Seattle, WA 98195, USA

b Department of Electrical Engineering, University of California-Santa Cruz, Santa Cruz, CA 95064, USA
E-mail: mrolandi@ucsc.edu

c Biomaterials Innovation Research Center, Division of Biomedical Engineering, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02139, USA
E-mail: alik@rics.bwh.harvard.edu

d Harvard-Massachusetts Institute of Technology Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA

e Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA

f Department of Bioindustrial Technologies, College of Animal Bioscience and Technology, Konkuk University, Hwayang-dong, Gwangjin-gu, Seoul 143-701, Republic of Korea

g Department of Physics, King Abdulaziz University, Jeddah 21569, Saudi Arabia

h Department of Chemical Engineering, Northeastern University, Boston, MA, USA
E-mail: n.annabi@neu.edu

Abstract

We demonstrate the formation of ultrastrong and flexible hydrogels via self-assembly of chitin nanofibers in the presence of gelatin methacryloyl. We tune the mechanical properties of the hydrogel using the chitin nanofiber content and show proof-of-concept applications in engineering vascular tissues.

Graphical abstract: Ultrastrong and flexible hybrid hydrogels based on solution self-assembly of chitin nanofibers in gelatin methacryloyl (GelMA)

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Article information

DOI
https://doi.org/10.1039/C6TB00021E
Article type
Communication
Submitted
06 Jan 2016
Accepted
23 Feb 2016
First published
23 Feb 2016

J. Mater. Chem. B, 2016,4, 2539-2543

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Ultrastrong and flexible hybrid hydrogels based on solution self-assembly of chitin nanofibers in gelatin methacryloyl (GelMA)

P. Hassanzadeh, M. Kazemzadeh-Narbat, R. Rosenzweig, X. Zhang, A. Khademhosseini, N. Annabi and M. Rolandi, J. Mater. Chem. B, 2016, 4, 2539 DOI: 10.1039/C6TB00021E

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