Issue 23, 2016
From the journal:

Journal of Materials Chemistry B

An ultrathin graphitic carbon nitride nanosheet: a novel inhibitor of metal-induced amyloid aggregation associated with Alzheimer's disease†

Meng Li,ab   Yijia Guan,ab   Chao Ding,ab   Zhaowei Chen,ab   Jinsong Rena  and  Xiaogang Qu*a  

* Corresponding authors

a Laboratory of Chemical Biology and State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, China
E-mail: xqu@ciac.ac.cn

b University of Chinese Academy of Sciences, Beijing, 100039, China

Abstract

Herein we report that a g-C3N4 nanosheet can act as a nanochelator to inhibit Cu2+ induced Aβ aggregation and disassemble the preformed Aβ–Cu2+ aggregates.

Graphical abstract: An ultrathin graphitic carbon nitride nanosheet: a novel inhibitor of metal-induced amyloid aggregation associated with Alzheimer's disease

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Article information

DOI
https://doi.org/10.1039/C6TB01215A
Article type
Communication
Submitted
15 Feb 2016
Accepted
16 May 2016
First published
17 May 2016

J. Mater. Chem. B, 2016,4, 4072-4075

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An ultrathin graphitic carbon nitride nanosheet: a novel inhibitor of metal-induced amyloid aggregation associated with Alzheimer's disease

M. Li, Y. Guan, C. Ding, Z. Chen, J. Ren and X. Qu, J. Mater. Chem. B, 2016, 4, 4072 DOI: 10.1039/C6TB01215A

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