Issue 42, 2016

A redox-responsive theranostic agent for target-specific fluorescence imaging and photodynamic therapy of EGFR-overexpressing triple-negative breast cancers

Abstract

A redox-responsive specific theranostic agent was developed by the conjugation of photosensitizers with the tryptophan-containing GE11 peptide via a cleavable disulfide linker. It showed a potential utility for the target-cell-specific activatable fluorescence imaging and photodynamic therapy of triple-negative breast cancers.

Graphical abstract: A redox-responsive theranostic agent for target-specific fluorescence imaging and photodynamic therapy of EGFR-overexpressing triple-negative breast cancers

Supplementary files

Article information

Article type
Communication
Submitted
20 Jun 2016
Accepted
11 Sep 2016
First published
13 Sep 2016

J. Mater. Chem. B, 2016,4, 6787-6790

A redox-responsive theranostic agent for target-specific fluorescence imaging and photodynamic therapy of EGFR-overexpressing triple-negative breast cancers

J. Kim, Y. Won, S. Goh and Y. Choi, J. Mater. Chem. B, 2016, 4, 6787 DOI: 10.1039/C6TB01519K

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