Issue 47, 2016

Photosensitizer-complexed polypyrrole nanoparticles for activatable fluorescence imaging and photodynamic therapy

Abstract

Here, we propose the use of photosensitizer-complexed polypyrrole nanoparticles (PCe4@HANP) as activatable theranostics. The fluorescence emission and singlet oxygen generation of PCe4@HANP were mostly turned off in the extracellular region, but became highly fluorescent and phototoxic upon internalization into cancer cells, enabling real-time near-infrared fluorescence imaging and photodynamic therapy of cancer.

Graphical abstract: Photosensitizer-complexed polypyrrole nanoparticles for activatable fluorescence imaging and photodynamic therapy

Supplementary files

Article information

Article type
Communication
Submitted
21 Sep 2016
Accepted
03 Nov 2016
First published
03 Nov 2016

J. Mater. Chem. B, 2016,4, 7545-7548

Photosensitizer-complexed polypyrrole nanoparticles for activatable fluorescence imaging and photodynamic therapy

D. Park, J. Kim and Y. Choi, J. Mater. Chem. B, 2016, 4, 7545 DOI: 10.1039/C6TB02461K

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