Biological effects, translocation, and metabolism of quantum dots in the nematode Caenorhabditis elegans

Abstract

Quantum dots (QDs), semiconductor nanomaterials with tiny light-emitting particles, act as important alternatives to conventional fluorescent dyes for biomedical imaging. With the increased tendency towards QD applications, concerns about the likelihood of adverse health impacts from exposure to QDs have also received attention. The nematode Caenorhabditis elegans is an important non-mammalian alternative model for the toxicological study of environmental toxicants including engineered nanomaterials. In this review, we summarize recent progress on the biological effects, translocation, and metabolism of QDs in the in vivo assay system of C. elegans. Moreover, certain perspectives or suggestions are further raised for the future toxicological study of QDs in nematodes.