Issue 3, 2017
From the journal:

Analyst

Utility of neurological smears for intrasurgical brain cancer diagnostics and tumour cell percentage by DESI-MS†

V. Pirro, ORCID logo a   A. K. Jarmusch,a   C. M. Alfaro,a   E. M. Hattab,*b   A. A. Cohen-Gadol*c  and  R. Graham Cooks*a  

* Corresponding authors

a Department of Chemistry, Purdue University, West Lafayette, IN, USA
E-mail: cooks@purdue.edu

b Department of Pathology and Laboratory Medicine, University of Louisville, Louisville, KY, USA
E-mail: eyas.hattab@louisville.edu

c Department of Neurological Surgery, Indiana University School of Medicine, Indianapolis, IN, USA
E-mail: acohenmd@gmail.com

Abstract

Analysis of neurological smears by desorption electrospray ionization mass spectrometry (DESI-MS) is an emerging diagnostic strategy for intraoperative consultation in brain tumor resection. DESI-MS allows rapid sampling while providing accurate diagnostic information. We assess the chemical homogeneity of neurological smears using DESI-MS imaging and the quality of rapid DESI-MS diagnosis.

Graphical abstract: Utility of neurological smears for intrasurgical brain cancer diagnostics and tumour cell percentage by DESI-MS

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C6AN02645A
Article type
Communication
Submitted
12 Dec 2016
Accepted
12 Jan 2017
First published
12 Jan 2017

Analyst, 2017,142, 449-454

Permissions

Request permissions

Utility of neurological smears for intrasurgical brain cancer diagnostics and tumour cell percentage by DESI-MS

V. Pirro, A. K. Jarmusch, C. M. Alfaro, E. M. Hattab, A. A. Cohen-Gadol and R. G. Cooks, Analyst, 2017, 142, 449 DOI: 10.1039/C6AN02645A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements