Issue 24, 2017
From the journal:

Analyst

A ratiometric mitochondria-targeting two-photon fluorescent probe for imaging of nitric oxide in vivo†

Xinyue Zhu, ORCID logo ‡a   Jin-Quan Chen, ORCID logo ‡a   Chen Ma,a   Xiaoyan Liu,a   Xiao-Ping Cao ORCID logo a  and  Haixia Zhang ORCID logo *a  

* Corresponding authors

a State Key Laboratory of Applied Organic Chemistry, Key Laboratory of Nonferrous Metals Chemistry and Resources Utilization of Gansu Province, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, China
E-mail: zhanghx@lzu.edu.cn
Fax: +86-931-8912582
Tel: +86-931-8912058

Abstract

A two-photon ratiometric fluorescent probe (Mito-N) has been developed for monitoring mitochondrial nitric oxide (NO) in vivo. Mito-N exhibited excellent selectivity and sensitivity toward NO among various ROS/RNS. The successful two-photon imaging of mitochondrial NO proved that Mito-N is a powerful noninvasive imaging tool in living systems.

Graphical abstract: A ratiometric mitochondria-targeting two-photon fluorescent probe for imaging of nitric oxide in vivo

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Article information

DOI
https://doi.org/10.1039/C7AN01461A
Article type
Communication
Submitted
04 Sep 2017
Accepted
02 Nov 2017
First published
06 Nov 2017

Analyst, 2017,142, 4623-4628

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A ratiometric mitochondria-targeting two-photon fluorescent probe for imaging of nitric oxide in vivo

X. Zhu, J. Chen, C. Ma, X. Liu, X. Cao and H. Zhang, Analyst, 2017, 142, 4623 DOI: 10.1039/C7AN01461A

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