Gd2O3 and GH combined with red blood cells to improve the sensitivity of contrast agents for cancer targeting MR imaging

Kunchi Zhang; Yi Cao; Ye Kuang; Min Liu; Yang Chen; Zhili Wang; Shanni Hong; Jine Wang; Renjun Pei

doi:10.1039/C6BM00627B

You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page.

Gd₂O₃ and GH combined with red blood cells to improve the sensitivity of contrast agents for cancer targeting MR imaging†

Kunchi Zhang,^a Yi Cao,^a Ye Kuang,^a Min Liu,*^a Yang Chen,^a Zhili Wang,^a Shanni Hong,^a Jine Wang^a and Renjun Pei*^a

Author affiliations

* Corresponding authors

^a Key Laboratory of Nano-Bio Interface, Division of Nanobiomedicine, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou, China
E-mail: rjpei2011@sinano.ac.cn
Tel: +86-512-62872776

Abstract

Herein, we fabricated efficient MR imaging probes by incorporating gadolinium oxide nanoparticles (Gd₂O₃) and gadolinium hybrid nanoparticles (GH) within RBCs. The Gd₂O₃ and GH encapsulated in the RBCs exhibited high relaxation rates and revealed high sensitivity for T₁ MR imaging.

Download options Please wait...

Supplementary files

Supplementary information PDF (356K)

Article information

DOI: https://doi.org/10.1039/C6BM00627B
Article type: Communication
Submitted: 08 Sep 2016
Accepted: 02 Nov 2016
First published: 14 Nov 2016

Download Citation

Biomater. Sci., 2017,5, 46-49

Permissions

Request permissions

Gd₂O₃ and GH combined with red blood cells to improve the sensitivity of contrast agents for cancer targeting MR imaging

K. Zhang, Y. Cao, Y. Kuang, M. Liu, Y. Chen, Z. Wang, S. Hong, J. Wang and R. Pei, Biomater. Sci., 2017, 5, 46 DOI: 10.1039/C6BM00627B

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Social activity

Fetching data from CrossRef.
This may take some time to load.

Biomaterials Science