Issue 3, 2017
From the journal:

Chemical Communications

Fluorescence detection of endogenous bisulfite in liver cancer cells using an effective ESIPT enhanced FRET platform†

Dong-Peng Li,a   Zhao-Yang Wang,b   Hao Su,a   Jun-Ying Miao*b  and  Bao-Xiang Zhao*a  

* Corresponding authors

a School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, P. R. China
E-mail: bxzhao@sdu.edu.cn
Fax: +86 531 88564464
Tel: +86 531 88366425

b Institute of Developmental Biology, School of Life Science, Shandong University, Jinan 250100, P. R. China
E-mail: miaojy@sdu.edu.cn

Abstract

Probe L-HF1, which featured large (pseudo) Stokes shifts and high FRET efficiency, was designed on a new ESIPT enhanced FRET platform for the detection of HSO3−/SO32−. L-HF1 could detect endogenous bisulfite in HepG2 cells but not in L-02 cells, implying the different bisulfite levels in normal and cancer cells of liver.

Graphical abstract: Fluorescence detection of endogenous bisulfite in liver cancer cells using an effective ESIPT enhanced FRET platform

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Article information

DOI
https://doi.org/10.1039/C6CC06459K
Article type
Communication
Submitted
04 Aug 2016
Accepted
29 Nov 2016
First published
02 Dec 2016

Chem. Commun., 2017,53, 577-580

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Fluorescence detection of endogenous bisulfite in liver cancer cells using an effective ESIPT enhanced FRET platform

D. Li, Z. Wang, H. Su, J. Miao and B. Zhao, Chem. Commun., 2017, 53, 577 DOI: 10.1039/C6CC06459K

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