Issue 1, 2017

Co-delivery of all-trans-retinoic acid enhances the anti-metastasis effect of albumin-bound paclitaxel nanoparticles

Abstract

Co-delivery of all-trans-retinoic acid and paclitaxel using albumin-bound nanoparticles demonstrated a significantly improved anti-metastatic effect to breast cancer both in vitro and in vivo. Notably, the co-delivery nanoparticles exhibited more pronounced therapeutic effects than the combination of two free drugs or two HSA loaded single drugs.

Graphical abstract: Co-delivery of all-trans-retinoic acid enhances the anti-metastasis effect of albumin-bound paclitaxel nanoparticles

Associated articles

Supplementary files

Article information

Article type
Communication
Submitted
09 Oct 2016
Accepted
23 Nov 2016
First published
05 Dec 2016

Chem. Commun., 2017,53, 212-215

Co-delivery of all-trans-retinoic acid enhances the anti-metastasis effect of albumin-bound paclitaxel nanoparticles

H. Huang, H. Shi, J. Liu, Y. Min, Y. Wang, A. Z. Wang, J. Wang and Y. Liu, Chem. Commun., 2017, 53, 212 DOI: 10.1039/C6CC08146K

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