A DNA kinetics competition strategy of hybridization chain reaction for molecular information processing circuit construction

Weiyang Tang; Qichen Huang; Zhenjie Yang; Qiwei Zheng; Lihong Wang; Junmin Zhang; Liang Chen; Xuechang Zhou; Yizhen Liu; Jiming Hu

doi:10.1039/C6CC08472A

A DNA kinetics competition strategy of hybridization chain reaction for molecular information processing circuit construction†

Weiyang Tang,‡^a Qichen Huang,‡^a Zhenjie Yang,‡^a Qiwei Zheng,^a Lihong Wang,^a Junmin Zhang,^a Liang Chen,^b Xuechang Zhou,

^a Yizhen Liu

*^a and Jiming Hu^c

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* Corresponding authors

^a College of Chemistry and Environmental Engineering, Shenzhen University, China
E-mail: yzliu@szu.edu.cn

^b College of Information Engineering, Shenzhen University, China

^c Key Laboratory of Analytical Chemistry for Biology and Medicine, Ministry of Education, College of Chemistry and Molecular Sciences, Wuhan University, China

Abstract

Herein we propose a hybridization chain reaction based kinetics competition strategy able to recognize the combination/sequence of input signals. Further, a DNA priority encoder and a keypad lock were constructed. This strategy allowed us to develop a one-pot assay that can automatically and smartly respond to multiple inputs.

Chemical Communications

A DNA kinetics competition strategy of hybridization chain reaction for molecular information processing circuit construction†

Abstract

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A DNA kinetics competition strategy of hybridization chain reaction for molecular information processing circuit construction

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