Issue 7, 2017
From the journal:

Chemical Communications

Tumor-cell targeting polydiacetylene micelles encapsulated with an antitumor drug for the treatment of ovarian cancer†

Defan Yao,a   Shang Li,a   Xiaomin Zhu,a   Junchen Wu*a  and  He Tiana  

* Corresponding authors

a Key Labs for Advanced Materials and Institute of Fine Chemicals, East China University of Science and Technology, Shanghai 200237, China
E-mail: jcwu@ecust.edu.cn
Fax: +86 21 6425 2288
Tel: +86 21 6425 3674

Abstract

Peptide functionalized polydiacetylene (PDA) micelles encapsulated with camptothecin (CPT) kill ovarian cancer cells by the lysosome release of anticancer drug CPT. Moreover, the sub-30 nm PDA micelles penetrate efficiently into a tumor for enhanced therapeutic efficacy.

Graphical abstract: Tumor-cell targeting polydiacetylene micelles encapsulated with an antitumor drug for the treatment of ovarian cancer

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Article information

DOI
https://doi.org/10.1039/C6CC08581D
Article type
Communication
Submitted
25 Oct 2016
Accepted
05 Dec 2016
First published
20 Dec 2016

Chem. Commun., 2017,53, 1233-1236

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Tumor-cell targeting polydiacetylene micelles encapsulated with an antitumor drug for the treatment of ovarian cancer

D. Yao, S. Li, X. Zhu, J. Wu and H. Tian, Chem. Commun., 2017, 53, 1233 DOI: 10.1039/C6CC08581D

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