A fluorogenic molecular nanoprobe with an engineered internal environment for sensitive and selective detection of biological hydrogen sulfide

Myung Kim; Young Hun Seo; Youngsun Kim; Jeongyun Heo; Woo-Dong Jang; Sang Jun Sim; Sehoon Kim

doi:10.1039/C6CC09696D

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A fluorogenic molecular nanoprobe with an engineered internal environment for sensitive and selective detection of biological hydrogen sulfide†

Myung Kim,‡^ab Young Hun Seo,‡^ac Youngsun Kim,^a Jeongyun Heo,^a Woo-Dong Jang,^c Sang Jun Sim^b and Sehoon Kim

*^a

Author affiliations

* Corresponding authors

^a Center for Theragnosis, Korea Institute of Science and Technology (KIST), 39-1 Hawolgok-dong, Seongbuk-gu, Seoul 136-791, Korea
E-mail: sehoonkim@kist.re.kr

^b Department of Chemical & Biological Engineering, Korea University, Seoul 136-713, Korea

^c Department of Chemistry, Yonsei University, 50 Yonsei-ro, Seodaemungu, Seoul 120-749, Korea

Abstract

A nanoreactor approach based on the amphiphilic assembly of various molecules offers a chance to finely engineer the internal reaction medium to enable highly selective and sensitive detection of H₂S in biological media, being useful for microscopic imaging of cellular processes and in vitro diagnostics with blood samples.

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Article information

DOI: https://doi.org/10.1039/C6CC09696D
Article type: Communication
Submitted: 06 Dec 2016
Accepted: 25 Jan 2017
First published: 26 Jan 2017

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Chem. Commun., 2017,53, 2275-2278

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A fluorogenic molecular nanoprobe with an engineered internal environment for sensitive and selective detection of biological hydrogen sulfide

M. Kim, Y. H. Seo, Y. Kim, J. Heo, W. Jang, S. J. Sim and S. Kim, Chem. Commun., 2017, 53, 2275 DOI: 10.1039/C6CC09696D

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Chemical Communications

A fluorogenic molecular nanoprobe with an engineered internal environment for sensitive and selective detection of biological hydrogen sulfide†

Abstract

Supplementary files

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A fluorogenic molecular nanoprobe with an engineered internal environment for sensitive and selective detection of biological hydrogen sulfide

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