Issue 12, 2017

Copper-mediated oxysulfonylation of alkenyl oximes with sodium sulfinates: a facile synthesis of isoxazolines featuring a sulfone substituent

Abstract

A novel and efficient Cu(OAc)2-mediated oxysulfonylation of alkenyl oximes with sodium sulfonates was developed. The reactions are easy to conduct, occur under mild conditions, and form a broad range of sulfone-substituted isoxazolines in good yields.

Graphical abstract: Copper-mediated oxysulfonylation of alkenyl oximes with sodium sulfinates: a facile synthesis of isoxazolines featuring a sulfone substituent

Supplementary files

Article information

Article type
Communication
Submitted
05 Jan 2017
Accepted
23 Jan 2017
First published
24 Jan 2017

Chem. Commun., 2017,53, 2056-2059

Copper-mediated oxysulfonylation of alkenyl oximes with sodium sulfinates: a facile synthesis of isoxazolines featuring a sulfone substituent

L. Wang, M. Chen, L. Qi, Z. Xu and W. Li, Chem. Commun., 2017, 53, 2056 DOI: 10.1039/C7CC00090A

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