Issue 30, 2017
From the journal:

Chemical Communications

Controlling transmembrane protein concentration and orientation in supported lipid bilayers†

P. Bao, ORCID logo a   M. L. Cartron,b   K. H. Sheikh,c   B. R. G. Johnson,a   C. N. Hunterb  and  S. D. Evans*a  

* Corresponding authors

a School of Physics & Astronomy, University of Leeds, UK
E-mail: s.d.evans@leeds.ac.uk

b Department of Molecular Biology & Biotechnology, University of Sheffield, UK

c School of Biomedical Science, University of Leeds, UK

Abstract

The trans-membrane protein – proteorhodopsin (pR) has been incorporated into supported lipid bilayers (SLB). In-plane electric fields have been used to manipulate the orientation and concentration of these proteins, within the SLB, through electrophoresis leading to a 25-fold increase concentration of pR.

Graphical abstract: Controlling transmembrane protein concentration and orientation in supported lipid bilayers

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C7CC01023K
Article type
Communication
Submitted
08 Feb 2017
Accepted
27 Mar 2017
First published
31 Mar 2017
This article is Open Access
Creative Commons BY license

Chem. Commun., 2017,53, 4250-4253

Permissions

Request permissions

Controlling transmembrane protein concentration and orientation in supported lipid bilayers

P. Bao, M. L. Cartron, K. H. Sheikh, B. R. G. Johnson, C. N. Hunter and S. D. Evans, Chem. Commun., 2017, 53, 4250 DOI: 10.1039/C7CC01023K

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements