Issue 26, 2017

Facile synthesis of chlorin bioconjugates by a series of click reactions

Abstract

A multifunctional chlorin platform appended with four short polyethylene glycols and a carboxylate-linker allows rapid conjugation to biotargeting motifs such as proteins and oligonucleotides. The stability and photophysical properties of the chlorin enable development of diagnostics, imaging, molecular tracking, and theranostics.

Graphical abstract: Facile synthesis of chlorin bioconjugates by a series of click reactions

Supplementary files

Article information

Article type
Communication
Submitted
16 Feb 2017
Accepted
28 Feb 2017
First published
02 Mar 2017

Chem. Commun., 2017,53, 3773-3776

Facile synthesis of chlorin bioconjugates by a series of click reactions

J. Gonzales, N. V. S. D. K. Bhupathiraju, W. Perea, H. Chu, N. Berisha, V. Bueno, N. Dodic, J. Rozenberg, N. L. Greenbaum and C. M. Drain, Chem. Commun., 2017, 53, 3773 DOI: 10.1039/C7CC01265A

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