Issue 39, 2017
From the journal:

Chemical Communications

Synthesis of new hydrophilic rhodamine based enzymatic substrates compatible with droplet-based microfluidic assays†

Johan Fenneteau, ORCID logo ‡a   Dany Chauvin,‡b   Andrew D. Griffiths,b   Clément Nizak ORCID logo *b  and  Janine Cossy*a  

* Corresponding authors

a Laboratoire de Chimie Organique, Institute of Chemistry, Biology and Innovation (CBI), UMR 8231, ESPCI Paris/CNRS, PSL Research University, 10 rue Vauquelin, 75231-Paris Cedex 05, France
E-mail: janine.cossy@espci.fr

b Laboratoire de Biochimie, Institute of Chemistry, Biology and Innovation (CBI), UMR 8231, ESPCI Paris/CNRS, PSL Research University, 10 rue Vauquelin, 75231-Paris Cedex 05, France
E-mail: clement.nizak@espci.fr

Abstract

Here we report the conception, synthesis and evaluation of new hydrophilic rhodamine-based enzymatic substrates for detection of peptidase activity compatible with high-throughput screening using droplet-based microfluidics.

Graphical abstract: Synthesis of new hydrophilic rhodamine based enzymatic substrates compatible with droplet-based microfluidic assays

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Article information

DOI
https://doi.org/10.1039/C7CC01506B
Article type
Communication
Submitted
25 Feb 2017
Accepted
25 Apr 2017
First published
25 Apr 2017

Chem. Commun., 2017,53, 5437-5440

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Synthesis of new hydrophilic rhodamine based enzymatic substrates compatible with droplet-based microfluidic assays

J. Fenneteau, D. Chauvin, A. D. Griffiths, C. Nizak and J. Cossy, Chem. Commun., 2017, 53, 5437 DOI: 10.1039/C7CC01506B

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