Issue 35, 2017

Lighting-up breast cancer cells by a near-infrared fluorescent probe based on KIAA1363 enzyme-targeting

Abstract

The first NIR KIAA1363-targeting probe, NB-AX, specifically and instantly featured an “off–on” switch upon gradual addition of KIAA1363 over all kinds of other biomolecules, and its detection limit was initially calculated to be 0.58 μg mL−1 (3δ/k). The probe was also able to be used in ultrafast distinguishing of breast cancer cells from normal cells in fluorescence imaging and applied in tissue imaging and tumor imaging in vivo.

Graphical abstract: Lighting-up breast cancer cells by a near-infrared fluorescent probe based on KIAA1363 enzyme-targeting

Supplementary files

Article information

Article type
Communication
Submitted
09 Mar 2017
Accepted
05 Apr 2017
First published
05 Apr 2017

Chem. Commun., 2017,53, 4857-4860

Lighting-up breast cancer cells by a near-infrared fluorescent probe based on KIAA1363 enzyme-targeting

J. Fan, S. Guo, S. Wang, Y. Kang, Q. Yao, J. Wang, X. Gao, H. Wang, J. Du and X. Peng, Chem. Commun., 2017, 53, 4857 DOI: 10.1039/C7CC01798G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements