Guided protein/cell patterning on superhydrophilic polymer brushes functionalized with mussel-inspired polydopamine coatings

Jianwen Hou; Tao Liu; Runhai Chen; Jingchuan Liu; Jiayue Chen; Chunyu Zhao; Ligang Yin; Chunming Li; Xiaodong Xu; Qiang Shi; Jinghua Yin

doi:10.1039/C7CC02460F

Guided protein/cell patterning on superhydrophilic polymer brushes functionalized with mussel-inspired polydopamine coatings†

Jianwen Hou,

^a Tao Liu,^b Runhai Chen,^a Jingchuan Liu,^a Jiayue Chen,^ac Chunyu Zhao,^a Ligang Yin,^c Chunming Li,^c Xiaodong Xu,^d Qiang Shi

*^a and Jinghua Yin*^a

Author affiliations

* Corresponding authors

^a State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, P. R. China
E-mail: shiqiang@ciac.ac.cn, yinjh@ciac.ac.cn

^b 306 Institute, Third Academy of China Aerospace Science and Industry Corp., Beijing 100074, P. R. China

^c Wego Holding Company Limited, Weihai 264210, P. R. China

^d Polymer Materials Research Center, College of Materials Science and Chemical Engineering, Harbin Engineering University, Harbin 150001, P. R. China

Abstract

A simple approach for preparing bicomponent polymer patterns was developed by coating polydopamine (PDA) on superhydrophilic poly(2-acryl-amido-2-methylpropane sulfonic acid) (PAMPS) brushes. Well-defined and versatile arrays of proteins and cells were achieved without harm to proteins and cells.

Chemical Communications

Guided protein/cell patterning on superhydrophilic polymer brushes functionalized with mussel-inspired polydopamine coatings†

Abstract

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Guided protein/cell patterning on superhydrophilic polymer brushes functionalized with mussel-inspired polydopamine coatings

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