A hyaluronidase/temperature dual-responsive supramolecular assembly based on the anionic recognition of calixpyridinium

Kui Wang; Jian-Hua Cui; Si-Yang Xing; Xiao-Wei Ren

doi:10.1039/C7CC02693E

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A hyaluronidase/temperature dual-responsive supramolecular assembly based on the anionic recognition of calixpyridinium†

Kui Wang,

*^a Jian-Hua Cui,^a Si-Yang Xing*^a and Xiao-Wei Ren^a

Author affiliations

* Corresponding authors

^a Tianjin Key Laboratory of Structure and Performance for Functional Molecules, Key Laboratory of Inorganic-Organic Hybrid Functional Materials Chemistry (Tianjin Normal University), Ministry of Education, College of Chemistry, Tianjin Normal University, Tianjin 300387, P. R. China
E-mail: hxxywk@mail.tjnu.edu.cn, hxxyxsy@mail.tjnu.edu.cn

Abstract

We have successfully constructed a supramolecular assembly based on the anionic recognition of calixpyridinium for the first time employing native biocompatible polysaccharide hyaluronan as the guest, which showed hyaluronidase-responsive disassembly and temperature-responsive morphological conversion from a nanosphere to a nanosquare upon increasing the temperature.

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Article information

DOI: https://doi.org/10.1039/C7CC02693E
Article type: Communication
Submitted: 07 Apr 2017
Accepted: 09 Jun 2017
First published: 09 Jun 2017

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Chem. Commun., 2017,53, 7517-7520

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A hyaluronidase/temperature dual-responsive supramolecular assembly based on the anionic recognition of calixpyridinium

K. Wang, J. Cui, S. Xing and X. Ren, Chem. Commun., 2017, 53, 7517 DOI: 10.1039/C7CC02693E

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Chemical Communications

A hyaluronidase/temperature dual-responsive supramolecular assembly based on the anionic recognition of calixpyridinium†

Abstract

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Article information

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A hyaluronidase/temperature dual-responsive supramolecular assembly based on the anionic recognition of calixpyridinium

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