Catalyst-free N-formylation of amines using BH3NH3 and CO2 under mild conditions

Abstract

The catalyst-free N-formylation of amines using CO₂ as the C₁ source and BH₃NH₃ as the reductant has been developed for the first time. The corresponding formylated products of both primary and secondary amines are obtained in good to excellent yields (up to 96% of isolated yield) under mild conditions.