Issue 82, 2017
From the journal:

Chemical Communications

Stereoselective synthesis of bicyclo[3.n.1]alkenone frameworks by Lewis acid-catalysis†

Stalin R. Pathipati, ORCID logo a   Lars Eriksson ORCID logo b  and  Nicklas Selander ORCID logo *a  

* Corresponding authors

a Department of Organic Chemistry, Stockholm University, Arrhenius Laboratory, Stockholm, Sweden
E-mail: nicklas.selander@su.se

b Department of Materials and Environmental Chemistry, Stockholm University, Arrhenius Laboratory, Stockholm, Sweden

Abstract

An intermolecular cyclization of alkynyl enones with cyclic ketones for the synthesis of bicyclo[3.n.1]alkenones is reported. This protocol exhibits a high functional group tolerance and provides access to a variety of bicyclic systems found as skeletons in many natural products.

Graphical abstract: Stereoselective synthesis of bicyclo[3.n.1]alkenone frameworks by Lewis acid-catalysis

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Article information

DOI
https://doi.org/10.1039/C7CC06400D
Article type
Communication
Submitted
15 Aug 2017
Accepted
04 Sep 2017
First published
02 Oct 2017
This article is Open Access
Creative Commons BY license

Chem. Commun., 2017,53, 11353-11356

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Stereoselective synthesis of bicyclo[3.n.1]alkenone frameworks by Lewis acid-catalysis

S. R. Pathipati, L. Eriksson and N. Selander, Chem. Commun., 2017, 53, 11353 DOI: 10.1039/C7CC06400D

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