Issue 83, 2017

The design of peptide-grafted graphene oxide targeting the actin cytoskeleton for efficient cancer therapy

Abstract

Graphene oxide (GO) nanosheets grafted with actin targeting and cell penetrating peptides were designed. The nanosheets were able to severely disrupt the organization of the tumor actin cytoskeleton, exhibiting excellent antitumor activity and high tumor specificity. This study implies the favorable potential of cancer therapies targeting the actin cytoskeleton.

Graphical abstract: The design of peptide-grafted graphene oxide targeting the actin cytoskeleton for efficient cancer therapy

Supplementary files

Article information

Article type
Communication
Submitted
20 Aug 2017
Accepted
26 Sep 2017
First published
26 Sep 2017

Chem. Commun., 2017,53, 11433-11436

The design of peptide-grafted graphene oxide targeting the actin cytoskeleton for efficient cancer therapy

Q. Yu, B. Zhang, J. Li and M. Li, Chem. Commun., 2017, 53, 11433 DOI: 10.1039/C7CC06537J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements