Issue 87, 2017
From the journal:

Chemical Communications

A two-photon excitable and ratiometric fluorogenic nitric oxide photoreleaser and its biological applications†

Xilei Xie,‡a   Jilin Fan,‡a   Muwen Liang,a   Yong Li,a   Xiaoyun Jiao,a   Xu Wang*a  and  Bo Tang ORCID logo *a  

* Corresponding authors

a College of Chemistry, Chemical Engineering and Materials Science, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Institute of Molecular and Nano Science, Shandong Normal University, Jinan 250014, P. R. China
E-mail: tangb@sdnu.edu.cn, wangxu@sdnu.edu.cn

Abstract

We report for the first time the development of a two-photon excitable NO photoreleaser, CNNO, for ratiometric imaging and tracking of NO release in live cells. CNNO exhibits the merits of spatiotemporal control in both the site-specific NO release in the selected cell culture region and the controllable vasodilation of mouse aorta ex vivo.

Graphical abstract: A two-photon excitable and ratiometric fluorogenic nitric oxide photoreleaser and its biological applications

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Article information

DOI
https://doi.org/10.1039/C7CC06820D
Article type
Communication
Submitted
30 Aug 2017
Accepted
12 Oct 2017
First published
12 Oct 2017

Chem. Commun., 2017,53, 11941-11944

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A two-photon excitable and ratiometric fluorogenic nitric oxide photoreleaser and its biological applications

X. Xie, J. Fan, M. Liang, Y. Li, X. Jiao, X. Wang and B. Tang, Chem. Commun., 2017, 53, 11941 DOI: 10.1039/C7CC06820D

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