Issue 88, 2017
From the journal:

Chemical Communications

NIR-absorbing dye functionalized hollow mesoporous silica nanoparticles for combined photothermal–chemotherapy†

Yuanyuan Zhang,ab   Qiuyu Qu,b   Xiang Caoa  and  Yanli Zhao ORCID logo *bc  

* Corresponding authors

a School of Chemical Engineering, Huaihai Institute of Technology, Lianyungang, P. R. China

b Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, 21 Nanyang Link, Singapore, Singapore
E-mail: zhaoyanli@ntu.edu.sg

c School of Materials Science and Engineering, Nanyang Technological University, Singapore 639798, Singapore

Abstract

Multifunctional hollow mesoporous silica nanoparticles were constructed by firstly loading with doxorubicin and then capping with disulfide linked β-cyclodextrin followed by complexation with adamantane functionalized indocyanine dye, showing improved anticancer efficacy through combined photothermal–chemotherapy.

Graphical abstract: NIR-absorbing dye functionalized hollow mesoporous silica nanoparticles for combined photothermal–chemotherapy

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Article information

DOI
https://doi.org/10.1039/C7CC07897H
Article type
Communication
Submitted
12 Oct 2017
Accepted
17 Oct 2017
First published
17 Oct 2017

Chem. Commun., 2017,53, 12032-12035

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NIR-absorbing dye functionalized hollow mesoporous silica nanoparticles for combined photothermal–chemotherapy

Y. Zhang, Q. Qu, X. Cao and Y. Zhao, Chem. Commun., 2017, 53, 12032 DOI: 10.1039/C7CC07897H

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