Phosphine-catalyzed Friedel–Crafts reaction of naphthols with para-quinone methides: expedient access to triarylmethanes

Tao Zhou; Shenhuan Li; Ben Huang; Cao Li; Yang Zhao; Jieqiong Chen; Aoling Chen; Yuanjin Xiao; Lu Liu; Junliang Zhang

doi:10.1039/C7OB00911A

Phosphine-catalyzed Friedel–Crafts reaction of naphthols with para-quinone methides: expedient access to triarylmethanes†

Tao Zhou,^a Shenhuan Li,^a Ben Huang,^a Cao Li,^a Yang Zhao,^a Jieqiong Chen,^a Aoling Chen,^a Yuanjin Xiao,^a Lu Liu

*^a and Junliang Zhang

*^a

Author affiliations

* Corresponding authors

^a School of Chemistry and Molecular Engineering, East China Normal University, 500 Dongchuan Road, Shanghai 200241, China
E-mail: lliu@chem.ecnu.edu.cn, jlzhang@chem.ecnu.edu.cn

Abstract

We developed a novel phosphine-catalyzed Friedel–Crafts reaction of naphthols with para-quinone methides (p-QMs). This reaction provided a promising method for the synthesis of triarylmethanes, which widely exist in natural products and in molecules which have been shown to have biological and pharmacological activity.

Organic & Biomolecular Chemistry

Phosphine-catalyzed Friedel–Crafts reaction of naphthols with para-quinone methides: expedient access to triarylmethanes†

Abstract

Associated articles

Supplementary files

Article information

Download Citation

Permissions

Phosphine-catalyzed Friedel–Crafts reaction of naphthols with para-quinone methides: expedient access to triarylmethanes

Social activity

Search articles by author

Spotlight

Advertisements