Issue 38, 2017
From the journal:

Organic & Biomolecular Chemistry

Thermoresponsive cyclodextrins with benzenesulfonamide showing tunable inhibition for carbonic anhydrase†

Apan Qian, ORCID logo a   Huang Shi,a   Runlang Zhu, ORCID logo a   Jiatao Yan, ORCID logo *a   Wen Li, ORCID logo a   Kun Liu ORCID logo a  and  Afang Zhang ORCID logo *a  

* Corresponding authors

a Laboratory of Polymer Chemistry, Department of Polymer Materials, College of Materials Science and Engineering, Shanghai University, Materials Building Room 447, Nanchen Street 333, Shanghai 200444, China
E-mail: jiataoyan@shu.edu.cn, azhang@shu.edu.cn.

Abstract

Monodisperse thermoresponsive cyclodextrins appended with benzenesulfonamides were demonstrated to reversibly regulate the enzymatic activity of carbonic anhydrase, which was found to be dependent on both scaffold effect and thermoresponsiveness.

Graphical abstract: Thermoresponsive cyclodextrins with benzenesulfonamide showing tunable inhibition for carbonic anhydrase

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Article information

DOI
https://doi.org/10.1039/C7OB02171B
Article type
Communication
Submitted
30 Aug 2017
Accepted
14 Sep 2017
First published
14 Sep 2017

Org. Biomol. Chem., 2017,15, 8028-8031

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Thermoresponsive cyclodextrins with benzenesulfonamide showing tunable inhibition for carbonic anhydrase

A. Qian, H. Shi, R. Zhu, J. Yan, W. Li, K. Liu and A. Zhang, Org. Biomol. Chem., 2017, 15, 8028 DOI: 10.1039/C7OB02171B

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