Issue 47, 2017

Acid-catalyzed reaction of 2-hydroxycyclobutanone with benzylic alcohols

Abstract

The acid-promoted syntheses of 2-(benzyloxy)cyclobutanones and bis(benzyloxy)dioxatricyclo decanes were achieved starting from 2-hydroxycyclobutanone and variously functionalized benzyl alcohols. The reaction sequences afforded the desired products in good to high yields and in a solvent-dependent chemoselective fashion.

Graphical abstract: Acid-catalyzed reaction of 2-hydroxycyclobutanone with benzylic alcohols

Supplementary files

Article information

Article type
Paper
Submitted
14 Oct 2017
Accepted
09 Nov 2017
First published
10 Nov 2017

Org. Biomol. Chem., 2017,15, 10053-10063

Acid-catalyzed reaction of 2-hydroxycyclobutanone with benzylic alcohols

A. Martis, A. Luridiana, A. Frongia, M. Arca, G. Sarais, D. J. Aitken, R. Guillot and F. Secci, Org. Biomol. Chem., 2017, 15, 10053 DOI: 10.1039/C7OB02545A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements